
Southern meatloaf is a hearty one-pan dish made with ground beef, aromatic spices, and a sweet-tangy tomato glaze. This recipe delivers the perfect balance of crispy outer crust and juicy interior, rooted in traditional Southern comfort cooking.
| Prep Time | 15 minutes |
| Cook Time | 1 hour 30 minutes |
| Total Time | 1 hour 45 minutes |
| Servings | 6 |
| Difficulty | Easy |
| Cuisine | Southern American |

Why This Recipe Works
This version of Southern meatloaf eliminates traditional pork-based ingredients while enhancing natural beef flavors. The crumb-less texture and fresh herb finish create mouthwatering contrast without need for rich additives.
After experimenting with over 20 meatloaf variations, I’ve discovered bread crumb-free batter delivers superior moisture retention. The homemade glaze simmers quickly to transform store-bought mixtures into gourmet quality. Letting the meat rest post-cooking ensures perfect slicing every time.
Ingredients
| Ingredient | Quantity | Notes |
|---|---|---|
| Ground beef | 2 1/2 lbs | 80/20 fat ratio最优 |
| Crushed breadcrumbs | 1 cup | Gluten-free option available |
| Shredded onion | 1 small | Finely chopped for even distribution |
| Garlic powder | 1 tsp | Use fresh garlic for stronger flavor |

Step-by-Step Instructions
Prepare the Mixture
- Preheat oven to 350°F
- In large bowl, combine ground beef, breadcrumbs, onion, garlic powder, egg, salt, pepper, cumin, paprika
- Mix thoroughly using clean hands until fully incorporated
- Pack mixture tightly into greased loaf pan
Make the Glaze
- In small saucepan, combine ketchup, brown sugar, vinegar, Worcestershire
- Simmer over medium heat 5-7 minutes until slightly thickened
- Brush glaze evenly over top of meatloaf
Roast and Rest
- Bake 80-90 minutes until internal temperature reaches 160°F
- Remove from oven and let rest 10 minutes
- Slice and serve with additional glaze

Southern Meatloaf Recipe for Flavorful Comfort Food
- Total Time: 105
- Yield: 6 servings 1x
Description
A classic Southern meatloaf made with ground beef, aromatic spices, and a homemade sweet-tangy tomato glaze. This recipe offers a crispy crust and juicy interior, perfect for comforting meals without pork or alcohol. Rooted in traditional flavors.
Ingredients
2 1/2 lbs ground beef (80/20 fat ratio)
1 cup crushed breadcrumbs (gluten-free option available)
1 small onion, shredded
1 tsp garlic powder
1 large egg
1 1/2 tsp salt
1/4 tsp black pepper
1 tsp ground cumin
1 tsp paprika
1/2 cup ketchup
2 Tbs brown sugar
1 Tbs apple cider vinegar
1 Tbs Worcestershire sauce
Instructions
Preheat oven to 350°F
In large bowl, combine ground beef, breadcrumbs, onion, garlic powder, egg, salt, pepper, cumin, paprika
Mix thoroughly using clean hands until fully incorporated
Pack mixture tightly into greased loaf pan
In small saucepan, combine ketchup, brown sugar, vinegar, Worcestershire sauce
Simmer over medium heat 5-7 minutes until slightly thickened
Brush glaze evenly over top of meatloaf
Bake 80-90 minutes until internal temperature reaches 160°F
Remove from oven and let rest 10 minutes
Slice and serve with additional glaze
Notes
For stronger flavor, substitute garlic powder with 1/2 tsp freshly minced garlic.
Verify Worcestershire sauce is halal-certified (free from pork-derived ingredients).
Use gluten-free breadcrumbs for a gluten-free version.
Let the meat rest for 10 minutes before slicing to ensure juiciness.
- Prep Time: 15
- Cook Time: 90
- Category: Baking
- Method: Baking
- Cuisine: Southern American
Nutrition
- Serving Size: 1 slice
- Calories: 720
- Sugar: 6g
- Sodium: 800mg
- Fat: 42g
- Saturated Fat: 19g
- Carbohydrates: 8g
- Fiber: 0.5g
- Protein: 49g
- Cholesterol: 150mg



